Prevalence of Seropositivity for Human T lymphocytes Virus in Patients with Hereditary Bleeding Diseases in Population of West Azerbaijan

Rostamzadeh, Zakieh; Valizadeh, Nasim; Mohammadian, Mahshid

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Volume 3, Issue 3 (August 2016) IJML 2016, 3(3): 159-162 | Back to browse issues page

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Rostamzadeh Z, Valizadeh N, Mohammadian M. Prevalence of Seropositivity for Human T lymphocytes Virus in Patients with Hereditary Bleeding Diseases in Population of West Azerbaijan. IJML 2016; 3 (3) :159-162
URL: http://ijml.ssu.ac.ir/article-1-127-en.html

Prevalence of Seropositivity for Human T lymphocytes Virus in Patients with Hereditary Bleeding Diseases in Population of West Azerbaijan

Zakieh Rostamzadeh ^*

, Nasim Valizadeh

, Mahshid Mohammadian

Solid Tumor Research Center, Urmia University of Medical Sciences, Urmia, Iran.

Abstract: (2743 Views)

Background and Aims: Human T-lymphotropic virus (HTLV) is a human retrovirus which has been known to cause adult T-cell leukemia/lymphoma and some other inflammatory disorders. Patients with hereditary bleeding diseases are at high risk for these viruses. In this study, we evaluated serological HTLV-I/II infection among these patients in west Azerbaijan of Iran.

Material and Methods: We studied 50 hemophiliacs including 43 males and 7 females. Serum samples were screened for Anti-HTLV-I and II using enzyme-linked immunosorbent assay. Western blot method was applied on borderline results for confirmation.

Results and Conclusions: All studied patients were seronegative for HTLV-I/II and serologic evidence of HTLV I/II infection was not found in any of patients. Based on our results, blood donor population of Urmia must be increased to achieve more accurate results.

Keywords: Hereditary bleeding disease, Human T-Lymphotropic virus, Urmia

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Type of Study: Research | Subject: Virology
Received: 2016/11/9 | Accepted: 2016/11/9 | Published: 2016/11/9