International Journal of Medical Laboratory
Shahid Sadoughi University of Medical Sciences
Tue, May 19, 2026
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Volume 12, Issue 2 (May 2025)
IJML 2025, 12(2): 97-104 |
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Astani A, Yadollahi A, Mousavi S A, Mirhosseini S B, Shamsi F, Akhoundi Meybodi Z. Adverse Effects of COVID-19 Vaccination Among Recipients in Yazd Province, 2021. IJML 2025; 12 (2) :97-104
URL: http://ijml.ssu.ac.ir/article-1-572-en.html
URL: http://ijml.ssu.ac.ir/article-1-572-en.html
Akram Astani 
, Abbas Yadollahi , Seyed Alireza Mousavi , Seyed Bagher Mirhosseini , Farimah Shamsi , Zohreh Akhoundi Meybodi *
, Abbas Yadollahi , Seyed Alireza Mousavi , Seyed Bagher Mirhosseini , Farimah Shamsi , Zohreh Akhoundi Meybodi *
Hematology and Oncology Research Center, Non-communicable Diseases Research Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran & Infectious Diseases Research Center, Shahid Sadoughi General Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Abstract: (25 Views)
Introduction: Following the rapid global spread of coronavirus disease 2019 (COVID-19), vaccines were developed and authorized for emergency use starting in early 2021. This study aimed to assess the potential adverse effects of COVID-19 vaccines in Yazd Province.
Materials and Methods: To address this objective, a descriptive-analytical cross-sectional study was conducted in 2021 among vaccinated individuals aged ≥18 years who reported post-vaccination symptoms. Adverse effects were recorded within 48 hours via phone or in-person follow-up and analyzed using SPSS v26.
Results: Of the 325 participants (51.7% female), the most common side effects were injection-site pain (58.5%), fever (36.3%), and allergic reactions (15.4%). Notably, the Sinopharm COVID-19 vaccine was the most commonly used (67.1%), followed by the AstraZeneca COVID-19 vaccine (18.5%). In addition, most participants (86.5%) received one dose. Importantly, no significant associations were found between adverse effects and age, gender, or vaccine type, except for rare cases of thrombocytopenia and seizures in younger individuals.
Conclusions: Taken together, these findings indicate that reported adverse effects were mostly mild and transient, supporting the overall safety of COVID-19 vaccines and encouraging public vaccination.
Materials and Methods: To address this objective, a descriptive-analytical cross-sectional study was conducted in 2021 among vaccinated individuals aged ≥18 years who reported post-vaccination symptoms. Adverse effects were recorded within 48 hours via phone or in-person follow-up and analyzed using SPSS v26.
Results: Of the 325 participants (51.7% female), the most common side effects were injection-site pain (58.5%), fever (36.3%), and allergic reactions (15.4%). Notably, the Sinopharm COVID-19 vaccine was the most commonly used (67.1%), followed by the AstraZeneca COVID-19 vaccine (18.5%). In addition, most participants (86.5%) received one dose. Importantly, no significant associations were found between adverse effects and age, gender, or vaccine type, except for rare cases of thrombocytopenia and seizures in younger individuals.
Conclusions: Taken together, these findings indicate that reported adverse effects were mostly mild and transient, supporting the overall safety of COVID-19 vaccines and encouraging public vaccination.
Type of Study: Research |
Subject:
Virology
Received: 2026/05/10 | Accepted: 2025/09/1 | Published: 2025/02/28
Received: 2026/05/10 | Accepted: 2025/09/1 | Published: 2025/02/28
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