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Showing 3 results for Meningitis
Evaluation of the Laboratory, Epidemiological and Clinical Characteristics of Meningitis Patients Admitted to the Hospitals of Yazd from 2009 to 2013
Mahmood Vakili , Zahra Rostami , Mohsen Mirzaei ,
Volume 3, Issue 4 (11-2016)
Abstract

Background and Aims: Since the epidemiological, clinical and experimental characteristics of meningitis are different for various locations, this study was conducted to investigate the characteristics of meningitis patients admitted to hospitals of Yazd in the 2009 to 2013.

Materials and Methods: In this cross-sectional and descriptive study, all 261 patients with meningitis were considered in Yazd hospitals in the years 2009 to 2013. The type of sampling method was census. The data were collected from patients’ files using special forms that were designed for this purpose.

Results: In this study, 158 men (60.5%) and 103 women (39.5%) were considered. Among the patients, 53 people (20.30%) were under one-year-old, 63 people (24.14%) were between one to seven-year-old, and 85 people (32.57%) were adult. Among 261 patients, 126 ones (48.28%) and 135 ones (51.72%) were hospitalized with a diagnosis of non-bacterial meningitis and bacterial meningitis respectively. Generally, the cultivations of just 4 people (1.5%) were positive. The percentage of neutrophils and lymphocytes, the amount of glucose and the protein of cerebrospinal fluid in bacterial and aseptic meningitis was significantly different (p<0.001), but the total number of white blood cells, red blood cells and lactate dehydrogenase levels were not significantly different between the two groups.

Conclusions: Since there is no significant difference between epidemiological characteristics and clinical symptoms in bacterial and no-bacterial meningitis, it seems that doing laboratory tests, despite aggressive, is the best practice for differentiating between types of meningitis and the fast performance of it could somewhat prevent the improper antibiotic therapy.


A Study on Bacterial Agents of Patients with Meningitis Referred to Afzalipour Hospital in Kerman, South East Iran
Mehrdad Farokhnia, Ali Hosseininasab, Mohadeseh Kamali, Bahman Pourabbas, Mehdi Taheri Sarvtin ,
Volume 9, Issue 1 (3-2022)
Abstract
Background and Aims: Identifying meningitis-causing bacteria play an important role in selecting the appropriate antibiotic vaccine and reducing the complications of meningitis. The present study aimed to identify the most common bacteria causing meningitis in patients referred to Afzalipour Hospital in Kerman.
Materials and Methods: In this cross-sectional study, 60 patients have participated. A 3-5 ml of cerebrospinal fluid specimens were obtained from each patient. Traditional and molecular methods identified bacterial agents.
Results and Conclusions: Twenty-eight females and thirty-two males participated in the study. Bacterial agents were recovered from 33.3% of the samples. Streptococcus pneumonia (65%), Staphylococcus epidermidis (10%), Klebsiella (10%), Enterococcus (5%), Escherichia coli (5%) and cocci gram-positive (5%) were the microbial agents identified in this study. In the present study, the detection rate of bacteria was low. Streptococcus pneumonia, especially the 18CFBA serotype, was the most common bacteria.

Evaluation of Biological Markers in Children's Cerebrospinal Fluid with Bacterial and Viral Meningitis
Mohammad Panji, Vahideh Behmard, Mehri Fallah Raoufi, Elnaz Sadat Mousavi Sadr Jadidi, Elham Rostami, Rahil Norbakhsh, Vajiheh Najafi, Tohid Moradi Gardeshi, Fahimeh Safizadeh, Haleh Barmaki,
Volume 10, Issue 3 (10-2023)
Abstract
Background and Aims: Cerebrospinal fluid (CSF) and blood biomarkers are widely evaluated as diagnostic tools to distinguish between bacterial meningitis and viral meningitis in emergency laboratory tests. So, this aimed to examine the levels of diagnostic parameters in blood and CSF to discriminate between bacterial and viral meningitis in young children referred to Khoy Hospital.
Materials and Methods: A total of 101 young children with meningitis were enrolled in this prospective study. The diagnosis of bacterial and viral meningitis was based on clinical features and laboratory findings.
Results: Of the 101 patients with meningitis, 18 (17.82%) were bacterial, and 83 (82.17%) were viral meningitis. The levels of CSF glucose and CSF/blood glucose ratio were significantly lower in the bacterial meningitis group than in the viral meningitis group (p < 0.01). In contrast, white blood cells count, CSF protein, interleukin-6, C-reactive protein, and ferritin levels were significantly higher in patients with bacterial meningitis compared to viral meningitis (p < 0.01). However, there was no difference between viral and bacterial meningitis groups concerning mean serum glucose.
Conclusion: This study suggests that decreased CSF glucose and CSF/blood glucose ratio and increased white blood cells count, CSF protein, ferritin, interleukin-6, and C-reactive protein combined with clinical symptoms can help better diagnosis of bacterial meningitis, especially in comparison with viral meningitis.

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