en ارزیابی روش های شناسایی آلودگی باکتریایی در فرآورده های پلاکتی خون شناسی و بانک خون Hematology & Blood Banking پژوهشي Research فرآورده های پلاکتی<span dir="LTR"> (PC) </span>کاربردهای بالینی گسترده ای دارند. &nbsp;<span title="Since PCs store in room temperature (between 20-24 °C), they are susceptible to bacterial contamination.">از آنجا که این فرآورده ها در دمای اتاق (بین 20 تا 24 درجه سانتیگراد) ذخیره می شوند، حساسیت زیادی به آلودگی های باکتریایی دارد.</span> <span title="There are varied approaches for identifying bacterial contamination in PCs.">&nbsp;روش های متنوعی برای شناسایی آلودگی باکتریایی در فرآورده های پلاکتی</span> وجود دارد<span dir="LTR">. </span><span title="These methods categorized into two groups: Firstly, culture based methods and secondly, non-culture based methods.">این روشها به دو دسته تقسیم می شوند: اول، روش های مبتنی بر کشت و دوم، روش های غیر مبتنی بر کشت</span><span dir="LTR">. </span><span title="Both of them have a couple of merits and demerits.">هر دو روش مزایا و معایب مختلفی دارند</span><span dir="LTR">. </span><span title="BacT/ALERT is a culture-based technique, which has been approved by the FDA.">BacT / ALERT </span>یک روش مبتنی بر کشت است که توسط<span dir="LTR"> FDA </span>تایید شده است<span dir="LTR">. </span><span title="Even though sensitivity and specificity of this method could be debatable and is not universal but this method consider as gold standard contemporary method and is far more dependable and superb in comparison with rest of contamination detection methods.">&nbsp;هر چند حساسیت و ویژگی این روش میتواند مورد سوال باشد، ولی به عنوان روش استاندارد طلایی (</span><span dir="LTR">Gold standard</span>) به حساب می آید و در مقایسه با دیگر روش های تشخیص آلودگی، اعتبار و کارایی بیشتری دارد. تصور می شود استفاده از روش های سریع نقش مهمی در تشخیص آلودگی باکتری ها در آینده ایفا کند <span dir="LTR">. </span><span title="Accordingly, this review aims to represent a summary of each method, which is used for bacterial contamination detection in PCs with detailed assessment of culture-based methods, specifically BacT/ALERT">بر این اساس، هدف از این مطالعه مروری ارائه خلاصه روش های شناسایی آلودگی باکتریایی در فرآورده های پلاکتی</span> با ارزیابی دقیق روش های مبتنی بر کشت به ویژه روش <span dir="LTR">&nbsp;BacT / ALERT</span>می باشد.<br> &nbsp; Platelet components (PCs) have widespread applications in clinical cases. Since PCs store in room temperature (between 20-24&deg;C), they are susceptible to bacterial contamination. There are varied approaches for identifying bacterial contamination in PCs. These methods categorized into two groups: Firstly, culture based methods and secondly, non-culture based methods. Both of them have a couple of merits and demerits. BacT/ALERT is a culture-based technique, which has been approved by the <a href="https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=17&cad=rja&uact=8&ved=0ahUKEwjq6vaThpjYAhVFLcAKHRVTDZ4QFghsMBA&url=https%3A%2F%2Fen.wikipedia.org%2Fwiki%2FFood_and_Drug_Administration&usg=AOvVaw2Nul0cvgx0xnDfq63j8xps" target="_blank">food and drug administration</a>. Although sensitivity and specificity of this method could be debatable and is not universal. This method is considered as gold standard contemporary method and it is far more dependable and superb in comparison with the contamination detection methods. It is assumed that, application of rapid methods play an important role in detection of bacterial contamination in the future. Accordingly, this study aimed to represent a summary of each method, which was used for bacterial contamination detection in PCs with detailed assessment of culture-based methods, specifically BacT/ALERT. فرآورده های پلاکتی, آلودگی باکتریایی, کشت باکتری, روش BacT/ALERT Bacterial contamination, BacT/ALERT, Culture based methods, Platelet components 232 245 http://ijml.ssu.ac.ir/browse.php?a_code=A-10-219-1&slc_lang=en&sid=1 Mohammad Ali Esmaili No Department of Hematology, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran. Farhad Razjou No Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran. Behzad Nazel Khosroshahi No Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran. Ali Amini No Department of Hematology, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran. Soodeh Namjoo No Department of Hematology, School of Allied Medical Sciences, Iran University of Medical Sciences, Tehran, Iran. peyman beigi No Faculty of Allied Medicine, Alborz University of Medical Sciences, Alborz, Iran. Mohammad Reza Rezvani Yes Department of Hematology, Faculty of Allied Medicine, Iran University of Medical Science, Tehran, Iran.