en باکتری شناسی Bactriology پژوهشي Research <strong>Background and Aims</strong><strong>:</strong> Uropathogenic<em> E.coli</em> is one of the most known causes of urinary tract infections, which may lead to a high rate of morbidity and mortality in high risk patients. In this regard, the virulence factors such as bacterial adhesion molecules have a critical role. The current study was intended to determine the molecular properties of adhesion genes in Uropathogenic <em>E.coli</em> strains isolated from hospitalized patients in Babol, north of Iran.<br> <strong>Materials and Methods</strong>: During a nine-months of study, 90 Uropathogenic <em>E</em>.<em>coli</em> strains were confirmed by differential biochemical and microbiological standard tests, antimicrobial susceptibility test, and molecular polymerase chain reaction assay were obtained for evaluating the frequency of adhesion genes.<br> <strong>Results: </strong>According to the results, the highest rate of resistance and susceptibility were belonged to <em>penicillin</em> <em>and imipenem respectively</em><em>. </em><em>On the other hand, the percentage of</em> <em>fimH</em> gene among other virulence genes was reported to be 66%.<br> <strong>Conclusions:</strong> The present study showed that a high level of uropathogenic<em> E</em>.<em>coli</em> isolates which harbored the adhesion factors may lead to distribution of multiple antimicrobial resistance strains.&nbsp; Escherichia coli, virulence factors, adhesion genes, antibiotic resistance, PCR Adhesion genes, Antibiotic resistance, Escherichia coli, Polymerase chain reaction, Virulence factors 271 277 http://ijml.ssu.ac.ir/browse.php?a_code=A-10-268-1&slc_lang=en&sid=1 Maryam Shafigh مریم شفیق maryamsh81@gmail.com No 1. Student Research Committee, Babol University of Medical Sciences, Babol, Iran گروه میکروب شناسی Fariba Akrami فریبا اکرمی fariba4820@gmail.com org/0000-0002-2167-4261 No 2. Department of Microbiology, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran گروه میکروب شناسی Amirmorteza Ebrahimzadeh Namvar امیرمرتضی ابراهیم زاده نامور Amirmorteza.namvar@gmail.com 0000-0003-2654-9643 Yes Department of Microbiology, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran گروه میکروب شناسی