fa باکتری شناسی Bactriology پژوهشي Research <div style="text-align: justify;"><span style="font-size:12pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:115%">Background and Aims: </span></span></b><span style="font-size:10.0pt"><span style="line-height:115%">Due to a wide variety of causes, various bacteria can acquire resistance to antibiotics. This study investigated the antibiotic susceptibility patterns of the etiologic bacterial agents of various infections in patients referred to three hospitals in Yazd city, Iran.</span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:10.0pt"><span style="line-height:115%">Materials and Methods</span></span></b><span style="font-size:10.0pt"><span style="line-height:115%">: A total of 336 clinical specimens including wound discharge, sputum, blood, bronchial fluid, pleural fluid, ascitic fluid, synovial fluid, stool, and trachea secretions were collected in three hospitals. Microbiological culturing in order to grow and identify the causative bacteria were performed. Antibiotic susceptibility determinations were done by the Kirby Bauer disk diffusion method. </span></span></span></span></span><br> <span style="font-size:12pt"><span style="line-height:115%"><span new="" roman="" style="font-family:" times=""><span style="color:black"><b><span style="font-size:10.0pt"><span style="line-height:115%"><span style="letter-spacing:-.3pt">Result</span></span></span></b><span style="font-size:10.0pt"><span style="line-height:115%"><span style="letter-spacing:-.3pt">:</span></span></span> <span style="font-size:10.0pt"><span style="line-height:115%"><span style="letter-spacing:-.3pt">Among all organisms isolated, <i>Escherchia coli, Staphylococcus. aureus, Staphylococcus. suprophyticus</i>, <i>Acinetobacter</i> <i>spp</i>., <i>Pseudomonas</i> <i>spp</i>.,</span></span></span><span style="font-size:10.0pt"><span style="line-height:115%"> <i>Klebsiella</i> <i>spp</i>., <i>Staphylococcus. epidermidis</i> and <i>Entrococcus</i> <i>spp</i>. were the most prevalent, respectively.</span></span><span style="font-size:10.0pt"><span style="line-height:115%"> The </span></span><i><span style="font-size:10.0pt"><span style="line-height:115%">Escherchia</span></span></i><i><span style="font-size:10.0pt"><span style="line-height:115%"> coli </span></span></i><span style="font-size:10.0pt"><span style="line-height:115%">isolates were the most antibiotic-resistant Gram-negative bacterium. </span></span><span style="font-size:10.0pt"><span style="line-height:115%">It seems that the same organisms recovered from different hospital wards show different antibiotic susceptibility patterns.</span></span></span></span></span></span><br> <b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">Conclusion</span></span></b><span style="font-size:10.0pt"><span new="" roman="" style="font-family:" times="">: The increased prevalence of resistant organisms in different hospitals may reflect a lack of proper antibiotic usage policy, resulting in the prolonged and indiscriminate use of antimicrobial agents.</span></span></div> Antibiotic susceptibility, Kirby bauer method, Microbiological culture 26 33 http://ijml.ssu.ac.ir/browse.php?a_code=A-10-287-2&slc_lang=fa&sid=1 Alireza Torki علیرضا ترکی 0000-0001-5822-0688 No Department of Microbiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran گروه میکروب شناسی، دانشکده پزشکی، دانشگاه علوم پزشکی شهید صدوقی، یزد، ایران Mahlagha Zahedi مه لقا زاهدی 0000-0001-9934-2104 No Department of Pathology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Nour Amirmozafari نور امیرمظفری 0000-0001-5186-8406 Yes Department of Microbiology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran