International Journal of Medical Laboratory

en Adverse Effects of COVID-19 Vaccination Among Recipients in Yazd Province, 2021 ویروس شناسی Virology پژوهشي Research <div style="text-align: justify;">Introduction: Following the rapid global spread of coronavirus disease 2019 (COVID-19), vaccines were developed and authorized for emergency use starting in early 2021. This study aimed to assess the potential adverse effects of COVID-19 vaccines in Yazd Province. Materials and Methods: To address this objective, a descriptive-analytical cross-sectional study was conducted in 2021 among vaccinated individuals aged ≥18 years who reported post-vaccination symptoms. Adverse effects were recorded within 48 hours via phone or in-person follow-up and analyzed using SPSS v26. Results: Of the 325 participants (51.7% female), the most common side effects were injection-site pain (58.5%), fever (36.3%), and allergic reactions (15.4%). Notably, the Sinopharm COVID-19 vaccine was the most commonly used (67.1%), followed by the AstraZeneca COVID-19 vaccine (18.5%). In addition, most participants (86.5%) received one dose. Importantly, no significant associations were found between adverse effects and age, gender, or vaccine type, except for rare cases of thrombocytopenia and seizures in younger individuals. Conclusions: Taken together, these findings indicate that reported adverse effects were mostly mild and transient, supporting the overall safety of COVID-19 vaccines and encouraging public vaccination.</div> Adverse effects, COVID-19, Vaccine 97 104 http://ijml.ssu.ac.ir/browse.php?a_code=A-10-1-65&slc_lang=en&sid=1 Akram Astani اکرم آستانی jdrzakhondie@yahoo.com No Department of Microbiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Department of Microbiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Abbas Yadollahi عباس یدالهی drzakhonrdie@yahoo.com No Infectious Diseases Research Center, Shahid Sadoughi General Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Infectious Diseases Research Center, Shahid Sadoughi General Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Seyed Alireza Mousavi سید علیرضا موسوی drgzakhondie@yahoo.com No Infectious Diseases Research Center, Shahid Sadoughi General Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Infectious Diseases Research Center, Shahid Sadoughi General Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Seyed Bagher Mirhosseini سید باقر میرحسینی hdrzakhondie@yahoo.com No Infectious Diseases Research Center, Shahid Sadoughi General Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Infectious Diseases Research Center, Shahid Sadoughi General Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Farimah Shamsi فریماه شمسی drzhakhondie@yahoo.com No Department of Biostatistics and Epidemiology, Shahid Sadoughi University of Medical Sciences, Iran Department of Biostatistics and Epidemiology, Shahid Sadoughi University of Medical Sciences, Iran Zohreh Akhoundi Meybodi زهره آخوندی میبدی drzaikhondie@yahoo.com Yes Hematology and Oncology Research Center, Non-communicable Diseases Research Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Hematology and Oncology Research Center, Non-communicable Diseases Research Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran