Prevalence of Hepatitis B Surface Antigen  and Associated Risk Factors with Hepatitis B Infection among Pregnant Women in Northeast of Iran

Pourafzali, Seyed Javad; Khaledi, Azad; Miri, Rahele; Shamsian, Seyed Ali Akbar; Rezaee, Seyed Abdolrahim; Piroozmand, Ahmad; Ghazvini, Kiarash

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Volume 5, Issue 3 (August 2018) IJML 2018, 5(3): 222-228 | Back to browse issues page

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Pourafzali S J, Khaledi A, Miri R, Shamsian S A A, Rezaee S A, Piroozmand A et al . Prevalence of Hepatitis B Surface Antigen and Associated Risk Factors with Hepatitis B Infection among Pregnant Women in Northeast of Iran. IJML 2018; 5 (3) :222-228
URL: http://ijml.ssu.ac.ir/article-1-217-en.html

Prevalence of Hepatitis B Surface Antigen and Associated Risk Factors with Hepatitis B Infection among Pregnant Women in Northeast of Iran

Seyed Javad Pourafzali

, Azad Khaledi

, Rahele Miri

, Seyed Ali Akbar Shamsian

, Seyed Abdolrahim Rezaee

, Ahmad Piroozmand

, Kiarash Ghazvini ^*

7 Antimicrobial Resistance Research Center, Department of Virology and Microbiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Abstract: (2364 Views)

Background and Aims: Almost 350 million people worldwide are carriers of hepatitis B virus. The rate of chronic carriers in Iran is about 3%. Therefore Iran is categorized as a country with moderate rate of infection with this virus. In developing countries, transmission from mother to fetus and newborn is considered as one of the main routes of transmission. So, this study investigated the prevalence of hepatitis B and its risk factors in pregnant women.
Material and Methods: In this descriptive cross-sectional study which has been done in 2010-2011, of 759 pregnant women referred to the Central Laboratory of ACCER and laboratory of Mashhad Ghaem hospital for HBsAg testing, after obtaining consent form, patients entered to the study with simple non-probability sampling, and a questionnaire was completed about demographic characteristics and related factors. Then data were analyzed by SPSS ver.13.
Results: The mean age of participants was 28.16 ± 4.8, the prevalence of HBsAg among pregnant women was reported 0.3%, and also because of finding only two cases of HBsAg positive, significant association was not found with socio-demographic factors such as; vaccination history of hepatitis B (P= 0.527) and risk factors including family history of hepatitis B or hepatitis C (P= 0.999).
Conclusions: Our study revealed that the prevalence rate of HBsAg positive among pregnant women is low. The prevalence of obtained HBsAg in this study compared to other studies from Iran is low, so, further studies with more cases are necessary to achieve real estimation of HBsAg positive among pregnant women.

Keywords: HBsAg, Pregnant women, Iran