International Journal of Medical Laboratory

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Zandi M, Soltani S, Fani M, Shafipour H, Abbasi S. The Comparison of Susceptibility to SARS-CoV-2 Infection between Pediatric and Adults. Int J Med Lab. 2021; 8 (4) :241-246
URL: http://ijml.ssu.ac.ir/article-1-415-en.html

SARS-CoV-2 causes coronavirus disease 2019 (COVID-19) and is responsible for the recent pandemic in the world. It has been recently recognized as a challenge for public health and a significant cause of severe illness in all age groups. Young children and older people are susceptible to SARS-CoV-2 infection. However, children usually present mild symptoms compared to adult patients. The relationship between age, severity, and COVID-19 transmission is compared to determine whether there is any reasonable relationship between age and COVID-19. It should be mentioned that some risk factors may increase the probability of developing severe COVID-19 by advancing age, such as pathophysiological changes in the respiratory system, angiotensin-converting enzyme 2 expression in the nasopharynx, and smoking. Susceptibility to SARS-CoV-2 infection is independent of age, but the mortality rate of COVID-19 depends on age.