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Volume 11, Issue 3 (August 2024)                   IJML 2024, 11(3): 217-230 | Back to browse issues page


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Owlia E, Pourrajab F. Aptamer-Based Lateral Flow Immunoassay for Detection of D-Dimer in the Blood. IJML 2024; 11 (3) :217-230
URL: http://ijml.ssu.ac.ir/article-1-545-en.html
Reproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Abstract:   (48 Views)

D-dimer is an essential biomarker for thrombotic disorders. Recent studies have developed aptamer-based lateral flow immunoassays (LFIAs) to detect D-dimer rapidly. This advanced platform merges the specificity of aptamers with lateral flow technology, enabling convenient point-of-care testing. Through optimization, assays have demonstrated high sensitivity and selectivity for D-dimer detection in clinical samples, making the platform a reliable marker for thrombosis. The platform offers a practical point-of-care diagnostic solution for thrombosis, with advantages such as rapid turnaround times, ease of use, and cost-effectiveness. Herein, this literature survey tries to discuss and underscore the effectiveness of aptamer-based LFIA as an innovative method for a rapid detection of D-dimer.

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Type of Study: Research | Subject: Biochemistry
Received: 2024/12/30 | Accepted: 2025/04/29 | Published: 2024/10/1

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